子宫内膜异位症患者生育问题的解决
魏代敏;孙梅;陈子江;
摘要(Abstract):
子宫内膜异位症(内异症)发病率在青春期及生育年龄妇女中较高,由于此病影响生育,所以从青春期开始,应对疑为内异症者尽早作出诊断和积极治疗;育龄妇女内异症患者应指导其尽早妊娠,已发生不孕者应积极治疗,以防止生育力进一步下降。目前的研究不支持单纯药物治疗。手术可提高各期患者的自然妊娠率,但手术对卵巢储备可能造成影响。体外受精-胚胎移植(in vitro fertilization-embryo transfer,IVF-ET)对中、重度内异症患者及手术治疗失败者有效。IVF前使用3~6个月的促性腺激素释放激素类似物(gonadotropin releasing hormone agonist,GnRHa)似可提高临床妊娠率。超促排卵(controlled ovary hyperstimulation,COH)对内异症病程的影响则需要进一步研究。
关键词(KeyWords): 子宫内膜异位症;不育,女性;手术;生殖技术,辅助;体外受精
基金项目(Foundation): 国家973基金资助项目(No:2006CB944004)
作者(Authors): 魏代敏;孙梅;陈子江;
DOI: 10.13283/j.cnki.xdfckjz.2009.05.018
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