卵母细胞玻璃化冻融21例临床分析Clinical analysis of oocyte vitrification in 21 cases
刘卫卫;孙莹璞;宋文妍;金海霞;苏迎春;郭艺红;
摘要(Abstract):
目的:探讨玻璃化冷冻方法在冷冻保存卵母细胞中的临床应用。方法:选择2007年10月~2009年1月在我中心行卵母细胞玻璃化冷冻,并于2008年1月~2009年4月行卵母细胞玻璃化解冻的21例移植周期,对其复苏率、受精率及临床妊娠率进行统计。结果:共冷冻203枚卵母细胞,解冻后存活137枚(67.5%,137/203),对其中98枚成熟卵母细胞行单精子卵浆内显微注射,76枚(77.6%,76/98)正常受精,8例(38.1%,8/21)获得临床妊娠,其中6例单胎妊娠,2例3胎妊娠,并进行了减胎术。目前,1例已成功分娩,1例早期流产,6例正在妊娠中。结论:玻璃化冻融卵母细胞是一种方便可行的方法,可以获得较高的临床妊娠率。
关键词(KeyWords): 卵母细胞冷冻;玻璃化;妊娠率
基金项目(Foundation):
作者(Authors): 刘卫卫;孙莹璞;宋文妍;金海霞;苏迎春;郭艺红;
DOI: 10.13283/j.cnki.xdfckjz.2010.03.011
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