体外受精-胚胎移植后双次血清β-HCG对妊娠结局的预测价值The predictive value of the double serum β-human chorionic gonadotropin in pregnancies outcome following IVF/ICSI-ET
于晓娜;孙莹璞;苏迎春;郭艺红;刘新贵;
摘要(Abstract):
目的:探讨体外受精-胚胎移植(IVF/ICSI-ET)后14天及18天双次血清β-人绒毛膜促性腺激素(β-HCG)预测妊娠结局的意义。方法:回顾分析2006年1月至2007年5月在我中心行新鲜周期IVF/ICSI-ET助孕后有14天及18天血清β-HCG水平的1154个周期,并追踪妊娠结局。结果:血清β-HCG水平与妊娠结局相关。移植后14天、18天继续妊娠组血清β-HCG值均高于不良妊娠组(P<0.05);而两组的上升幅度无显著性差异(P>0.05)。多胎组血清β-HCG值高于单胎组(P<0.05);单胎组血清β-HCG值高于流产组(P<0.05);流产组和异位妊娠组的血清β-HCG值均高于生化妊娠组(P<0.05);而流产组血清β-HCG值与异位妊娠组无显著性差异(P>0.05)。有233例患者移植14天抽血检测β-HCG<5IU/L后18天未抽血检测β-HCG,追踪随访有7例患者妊娠,早期流产率为85.71%(6/7),继续妊娠率为14.29%(1/7)。结论:IVF-ET后双次血清β-HCG值对早期妊娠结局有较好的预测价值,有助于临床及早期鉴别诊断。
关键词(KeyWords): 血清β-HCG;体外受精-胚胎移植;妊娠结局
基金项目(Foundation):
作者(Authors): 于晓娜;孙莹璞;苏迎春;郭艺红;刘新贵;
DOI: 10.13283/j.cnki.xdfckjz.2008.08.006
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