外阴阴道假丝酵母菌病严重程度影响因素的Logistic回归分析Logistic regression analysis of the factors related with severity of vulvovaginal candidiasis
刘晓娟;耿女;王辰;闫晔;范爱萍;韩姹;王颖梅;薛凤霞;
摘要(Abstract):
目的:分析外阴阴道假丝酵母菌病(VVC)疾病严重程度的相关影响因素。方法:将2011年8月2015年8月就诊于天津医科大学总医院普通妇科门诊的237例重度VVC患者及同期490例轻中度VVC患者作为研究对象进行病例对照研究。采用Logistic回归模型进行单因素及多因素分析。结果:(1)单因素分析显示,年龄≥30岁(OR=0.658,95%CI为0.4812015年8月就诊于天津医科大学总医院普通妇科门诊的237例重度VVC患者及同期490例轻中度VVC患者作为研究对象进行病例对照研究。采用Logistic回归模型进行单因素及多因素分析。结果:(1)单因素分析显示,年龄≥30岁(OR=0.658,95%CI为0.4810.899,P=0.009)、已婚(OR=0.560,95%CI为0.3940.899,P=0.009)、已婚(OR=0.560,95%CI为0.3940.794,P=0.001)、采用自然避孕法避孕(OR=0.588,95%CI为0.3590.794,P=0.001)、采用自然避孕法避孕(OR=0.588,95%CI为0.3590.965,P=0.036)、有妊娠史(OR=0.565,95%CI为0.4110.965,P=0.036)、有妊娠史(OR=0.565,95%CI为0.4110.777,P=0.000)、有阴道分娩史(OR=0.557,95%CI为0.3710.777,P=0.000)、有阴道分娩史(OR=0.557,95%CI为0.3710.835,P=0.005)是重度VVC的保护因素。白假丝酵母菌感染(OR=5.678,95%CI为2.1800.835,P=0.005)是重度VVC的保护因素。白假丝酵母菌感染(OR=5.678,95%CI为2.18014.789,P=0.000)是重度VVC的危险因素。对食物、药物或花草过敏(OR=1.713,95%CI为0.98214.789,P=0.000)是重度VVC的危险因素。对食物、药物或花草过敏(OR=1.713,95%CI为0.9822.988,P=0.058)是重度VVC的可疑危险因素。(2)多因素分析显示,白假丝酵母菌感染(OR=4.593,95%CI为1.7002.988,P=0.058)是重度VVC的可疑危险因素。(2)多因素分析显示,白假丝酵母菌感染(OR=4.593,95%CI为1.70012.414,P=0.003)以及对药物、食物或花草过敏(OR=2.172,95%CI为1.05912.414,P=0.003)以及对药物、食物或花草过敏(OR=2.172,95%CI为1.0594.458,P=0.034)是重度VVC的独立危险因素。结论:白假丝酵母菌感染以及对药物、食物或花草过敏是重度VVC的独立危险因素。
关键词(KeyWords): 外阴阴道假丝酵母菌病;严重程度;危险因素
基金项目(Foundation): 国家自然科学基金资助项目(No:81471419)
作者(Authors): 刘晓娟;耿女;王辰;闫晔;范爱萍;韩姹;王颖梅;薛凤霞;
DOI: 10.13283/j.cnki.xdfckjz.2016.05.001
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