刘晓娟;耿女;王辰;闫晔;范爱萍;韩姹;王颖梅;薛凤霞;

• 1:天津医科大学总医院妇产科

摘要(Abstract)：

目的:分析外阴阴道假丝酵母菌病(VVC)疾病严重程度的相关影响因素。方法:将2011年8月²015年8月就诊于天津医科大学总医院普通妇科门诊的237例重度VVC患者及同期490例轻中度VVC患者作为研究对象进行病例对照研究。采用Logistic回归模型进行单因素及多因素分析。结果:(1)单因素分析显示,年龄≥30岁(OR=0.658,95%CI为0.4812015年8月就诊于天津医科大学总医院普通妇科门诊的237例重度VVC患者及同期490例轻中度VVC患者作为研究对象进行病例对照研究。采用Logistic回归模型进行单因素及多因素分析。结果:(1)单因素分析显示,年龄≥30岁(OR=0.658,95%CI为0.481⁰.899,P=0.009)、已婚(OR=0.560,95%CI为0.3940.899,P=0.009)、已婚(OR=0.560,95%CI为0.394⁰.794,P=0.001)、采用自然避孕法避孕(OR=0.588,95%CI为0.3590.794,P=0.001)、采用自然避孕法避孕(OR=0.588,95%CI为0.359⁰.965,P=0.036)、有妊娠史(OR=0.565,95%CI为0.4110.965,P=0.036)、有妊娠史(OR=0.565,95%CI为0.411⁰.777,P=0.000)、有阴道分娩史(OR=0.557,95%CI为0.3710.777,P=0.000)、有阴道分娩史(OR=0.557,95%CI为0.371⁰.835,P=0.005)是重度VVC的保护因素。白假丝酵母菌感染(OR=5.678,95%CI为2.1800.835,P=0.005)是重度VVC的保护因素。白假丝酵母菌感染(OR=5.678,95%CI为2.180¹4.789,P=0.000)是重度VVC的危险因素。对食物、药物或花草过敏(OR=1.713,95%CI为0.98214.789,P=0.000)是重度VVC的危险因素。对食物、药物或花草过敏(OR=1.713,95%CI为0.982².988,P=0.058)是重度VVC的可疑危险因素。(2)多因素分析显示,白假丝酵母菌感染(OR=4.593,95%CI为1.7002.988,P=0.058)是重度VVC的可疑危险因素。(2)多因素分析显示,白假丝酵母菌感染(OR=4.593,95%CI为1.700¹2.414,P=0.003)以及对药物、食物或花草过敏(OR=2.172,95%CI为1.05912.414,P=0.003)以及对药物、食物或花草过敏(OR=2.172,95%CI为1.059⁴.458,P=0.034)是重度VVC的独立危险因素。结论:白假丝酵母菌感染以及对药物、食物或花草过敏是重度VVC的独立危险因素。

关键词(KeyWords)： 外阴阴道假丝酵母菌病;严重程度;危险因素

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(No:81471419)

作者(Authors): 刘晓娟;耿女;王辰;闫晔;范爱萍;韩姹;王颖梅;薛凤霞;

DOI: 10.13283/j.cnki.xdfckjz.2016.05.001

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