徐婧;刘延;丁晓毅;冯炜炜;

• 1:上海交通大学医学院附属瑞金医院

摘要(Abstract)：

目的:研究影响胎盘植入程度的临床危险因素,评估髂内动脉球囊预置技术在控制不同程度胎盘植入患者产后出血中的价值。方法:收集2012年1月至2019年6月于上海瑞金医院产科剖宫产终止妊娠的胎盘植入孕妇108例,根据胎盘植入肌层的深度分为粘连组(PA组)60例和重度植入组48例。采用单因素分析及多因素logistic回归分析影响胎盘植入程度的临床危险因素。重度植入组(胎盘植入PI组45例+穿透性胎盘PP组3例)中,22例术前诊断,行髂内动脉球囊预置,26例未行髂内动脉球囊预置。比较两组患者的年龄、孕周、住院费用、出血量、术后血红蛋白(Hb)变化情况、产后出血率、输血率、子宫切除率、新生儿窒息评分,以及晚期产后出血、产褥期感染及下肢深静脉血栓等并发症发生情况。结果:多因素分析显示,年龄、既往剖宫产术史和此次妊娠前置胎盘是影响胎盘植入严重程度的独立危险因素(P<0.05)。与未预置组比较,预置组的术后血红蛋白(Hb)下降少,产后出血率及术后输血率减少,差异均有统计学意义(P<0.05);两组的子宫切除率比较,差异无统计学意义(P>0.05)。远期随访48例重度植入患者,无晚期产后出血、产褥期感染及下肢深静脉血栓等并发症发生。结论:年龄、既往剖宫产术史和此次妊娠前置胎盘是影响胎盘植入严重程度的独立危险因素,需加强对此类孕妇的孕期监控。术前行髂内动脉球囊预置术,能明显减少重度胎盘植入患者剖宫产产后出血率,减少术后血红蛋白(Hb)下降及减少输血率,是控制出血的有效手段。

关键词(KeyWords)： 胎盘粘连;胎盘植入;胎盘穿透性植入;髂内动脉球囊介入技术

Abstract:

Keywords:

基金项目(Foundation): 上海市科学技术委员会科研项目计划(No:17411959594)

作者(Authors): 徐婧;刘延;丁晓毅;冯炜炜;

DOI: 10.13283/j.cnki.xdfckjz.2020.01.004

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