朱彩英;曹远奎;李燕云;陈丽梅;刁文静;谢锋;郭奇桑;宋昱;叶新红;吴琴姣;杜雪寒;罗雪珍;徐洁;刘晓霞;李昕;隋龙;

• 1:复旦大学附属妇产科医院宫颈疾病诊疗中心上海市生殖内分泌重点实验室
• 2:复旦大学附属妇产科医院妇科

摘要(Abstract)：

目的:评价红核妇洁洗液治疗单纯性外阴阴道假丝酵母菌病(VVC)的有效性和安全性。方法:2014年6月至2016年6月在复旦大学附属妇产科医院门诊募集单纯性VVC患者,随机分为研究组(红核妇洁洗液组)和对照组(硝酸咪康唑软胶囊组),分别在治疗前和治疗结束后1²周、4周、8周进行真菌检测、瘙痒评价、VVC评分、BV五项检测及安全性评估。结果:治疗后12周、4周、8周进行真菌检测、瘙痒评价、VVC评分、BV五项检测及安全性评估。结果:治疗后1²周,研究组和对照组的瘙痒阳性率、真菌阳性率、VVC评分均呈显著下降趋势,两组比较无显著差异。两组治疗后4周与基线相比,p H值、唾液酸苷酶、白细胞脂酶、脯氨酸氨基肽酶阳性率显著下降,但两组无显著差异。治疗后8周,研究组的白细胞脂酶阳性率、VVC评分显著低于对照组。两组患者在治疗前后血常规、生化指标、心电图等无显著差异,无明显不良反应。结论:红核妇洁洗液治疗单纯性VVC有效、安全,在临床上值得进一步应用。

关键词(KeyWords)： 单纯性外阴阴道假丝酵母菌病;红核妇洁洗液

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 朱彩英;曹远奎;李燕云;陈丽梅;刁文静;谢锋;郭奇桑;宋昱;叶新红;吴琴姣;杜雪寒;罗雪珍;徐洁;刘晓霞;李昕;隋龙;

DOI: 10.13283/j.cnki.xdfckjz.2017.06.006

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