刘红;房朝晖;王娟;吴小华;

• 1:河北医科大学第四医院妇瘤科
• 2:河北医科大学第四医院妇产科

摘要(Abstract)：

目的:研究溶血磷脂酸受体在人卵巢癌细胞系和人卵巢癌组织中蛋白的表达。方法:用免疫细胞化学和免疫组织化学法检测LPA1,LPA2和LPA3蛋白在人卵巢癌细胞系3AO、OVCAR3、SKOV3和人卵巢癌组织中的表达水平。结果:免疫细胞化学显示LPA1,LPA2和LPA3蛋白在人卵巢癌细胞系中均有表达;免疫组织化学显示LPA1蛋白在正常卵巢上皮和卵巢良性肿瘤中高表达,LPA2和LPA3蛋白在人卵巢癌组织中高表达。结论:LPA1,LPA2和LPA3在人卵巢癌细胞系和人卵巢癌组织中均有广泛表达;LPA2,LPA可能与卵巢癌的发生发展密切相关。

关键词(KeyWords)： 受体,溶血磷脂酸;卵巢肿瘤;细胞系

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金资助项目(No:30572093);; 河北省科学技术研究及发展计划指导性项目(No:0727611007)

作者(Authors): 刘红;房朝晖;王娟;吴小华;

DOI: 10.13283/j.cnki.xdfckjz.2008.10.016

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