Lynch综合征相关妇科肿瘤的临床思考
王轶英;王悦;宁燕;孔北华;郑文新;
摘要(Abstract):
<正>Lynch综合征(lynch syndrome,LS),又称遗传性非息肉状结直肠癌(hereditary non-polyposis color-ectal cancer,HNPCC),属常染色体显性遗传性疾病,由DNA错配修复(mismatch repair,MMR)基因突变引起,其发病率约占结直肠癌的2%~5%[1-2]。根据有无肠外肿瘤将LS分为Ⅰ型和Ⅱ型:Ⅰ型仅表现
关键词(KeyWords):
基金项目(Foundation):
作者(Authors): 王轶英;王悦;宁燕;孔北华;郑文新;
DOI: 10.13283/j.cnki.xdfckjz.2013.07.006
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