多囊卵巢综合征的遗传研究进展
陆湘
摘要(Abstract)：
多囊卵巢综合征 (PCOS)的家族聚集现象提示遗传因素的重要作用 ,遗传方式尚不肯定 ,可能为常染色体显性遗传。目前认为 ,PCOS复杂的临床表现和生化特征是多个基因和环境因素共同作用的结果 ,其中CYP11α和雄激素受体 (AR)基因的变异与PCOS的高雄激素血症相关 ,胰岛素基因 5′端可变数串连重复序列 (VNTR)则是PCOS的易感位点 ,但这些都有争议和分歧 ,需要更多的研究进一步发现和证实
关键词(KeyWords)： 多囊卵巢综合征;雄激素增多症;胰岛素抵抗
基金项目(Foundation):
作者(Author): 陆湘
DOI: 10.13283/j.cnki.xdfckjz.2003.06.022
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